Risk factors for new renal scarring in children with vesicoureteral reflux receiving continuous antibiotic prophylaxis

“This study aimed to analyze the clinical data of children receiving CAP treatment for VUR in our hospital from 2016 to 2019, with the purpose of summarizing the risk factors for new kidney scarring in children with VUR.”

“Previous studies have found that in children with VUR who use CAP intervention, high-level VUR, especially IV-V grade VUR, is an independent risk factor for NRS26. Mattoo et al.5 found in a prospective randomized controlled clinical study (RIVUR) that children with IV-V grade VUR were more likely to develop BT-UTI and renal scars, 24.2 and 1.88 times higher than those with I–III grade VUR, respectively. Sitarah Mathias et al.27 also found that patients with high-grade VUR patients were more likely than those with low-grade VUR patients to have renal scarring.”